NAT2
Some search terms matchedNAT2 encodes N-acetyltransferase 2, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story.
Also called: N-Acetyltransferase 2
Acetyla…
NOS3
Some search terms matchedNOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease.
Also c…
NQO1
Some search terms matchedNQO1 is the gene symbol used for NAD(P)H Quinone Oxidoreductase 1. This page connects its terminology with the topics in the Purser Wellness teaching library.
Also called: NAD(P)H Quinone Oxidoreductase 1
Quinone handling within the redox n…
NR3C1
Some search terms matchedNR3C1 encodes the glucocorticoid receptor, which helps tissues respond to cortisol and glucocorticoid medicines. Receptor genetics and measured cortisol levels answer different questions.
Also called: Nuclear Receptor Subfamily 3 Group C Me…
NR3C2
Some search terms matchedNR3C2 encodes the mineralocorticoid receptor, which responds to hormones such as aldosterone and helps regulate salt and fluid balance. It is distinct from the NR3C1 glucocorticoid receptor.
Also called: Mineralocorticoid Receptor / Nuclear…
NTRK2
Some search terms matchedNTRK2 encodes TrkB, a receptor involved in responding to neurotrophic signals such as BDNF. These signals support nervous-system function and plasticity. NTRK2 is not a phosphatidylserine absorption transporter.
Also called: Neurotrophic Re…
PEMT
Some search terms matchedMakes an enzyme involved in producing phosphatidylcholine, a component of cell membranes. Genetic findings alone do not establish a choline deficiency.
Also called: Phosphatidylethanolamine N-Methyltransferase, choline, phosphatidylcholine
…
PON1
Some search terms matchedPON1 appears in Dr.
Also called: Paraoxonase 1
A different part of antioxidant handling
PON1 appears in Dr. Purser’s redox and conversion teaching alongside GST and NQO1. The genetics reference discusses it in relation to handling particula…
PSEN1
Some search terms matchedPSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
PSEN2
Some search terms matchedPSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Also called:…
PTGS2
Some search terms matchedPTGS2, commonly called COX-2, encodes an enzyme involved in prostaglandin production. Prostaglandins participate in pain, fever and inflammatory signaling.
Also called: COX2, Cyclooxygenase 2
COX-2 and inflammatory prostaglandins
PTGS2, com…
SERPINE1
Some search terms matchedSERPINE1 encodes plasminogen activator inhibitor-1, or PAI-1, which helps regulate fibrinolysis: the process that breaks down clots. The source label PAI4G refers to this pathway rather than a separate gene.
Also called: PAI-1, PAI4G, Plasm…
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