Encodes an enzyme involved in fatty-acid metabolism.
Also called: Fatty Acid Desaturase 2 / D6D
The form of a fatty acid matters
Dr. Purser teaches FADS genes as a conversion pathway. FADS2 participates in a delta-6 desaturase step in fatty…
Dr.
Also called: Folate Hydrolase 1
Folate handling begins before remethylation
Dr. Purser’s genetic chapters include FOLH1 in folate handling. The earlier genetics reference explains its role in breaking down polyglutamated food folates in…
FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
Also called: Folate Receptor …
FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors.
Also called: Fat Mass and Obesity-…
Dr.
Also called: Fucosyltransferase 2
The mucosal and microbiome connection
Dr. Purser’s course places FUT2 in its gut–immune map. FUT2 concerns secretor biology and the surface environment of mucosal tissues, helping explain why it appears…
G6PC2 encodes a glucose-6-phosphatase-related protein expressed in pancreatic islet cells. Common variation is associated with differences in fasting glucose regulation; it is not the insulin receptor.
Also called: Glucose-6-Phosphatase Cat…
Dr.
Also called: Glutamate Decarboxylase 1
The glutamate-to-GABA connection
Dr. Purser’s course uses GAD/GABA teaching to explain a connection between excitatory and inhibitory signaling. GAD1 encodes an enzyme involved in producing GABA fr…
GAD2 belongs to the glutamate decarboxylase family discussed in the course’s GAD/GABA teaching.
Also called: Glutamate Decarboxylase 2
Another part of the GABA system
GAD2 belongs to the glutamate decarboxylase family discussed in the cours…
Dr.
Also called: Glutamate-Cysteine Ligase Catalytic Subunit
Making glutathione is a process
Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLC supplies the catalytic component of the first enzyme step in glutathione s…
Dr.
Also called: Glutamate-Cysteine Ligase Modifier Subunit
Making glutathione is a process
Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLM supplies the modifier component that helps regulate that same glutathione-s…
GDF5 encodes growth differentiation factor 5, a signaling protein involved in skeletal development, joint formation and cartilage biology. Its name does not mean a SNP measures the ability to build muscle.
Also called: Growth Differentiatio…
GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake.
Also called: Gamma-Gluta…
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