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Explore the NLRP3 sensor, inflammasome priming and activation, IL-1 beta, IL-18, and pyroptosis.

Explore volatile hypertension, autonomic regulation, monocytes, vascular inflammation, and how they may connect.

Could the signals controlling your health be working for you... or against you? Most people have never heard of cytokines, yet these powerful cellular messengers play a critical role in how your body responds to stress, inflammation, recov

A sudden spike in folate or homocysteine is rarely caused by supplements. It is most often the result of a hidden infection or minor injury triggering a cytokine surge. Identifying and treating the underlying source is the key to bringing l

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, pain and wellbeing.

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by triggering cytokine release. For some people, genetics or deficiencies cause a “fixed homocysteine rate,” meaning diet and vi

Homocysteine is a natural molecule your body makes, but when levels get too high it drives massive inflammation by triggering cytokine release. For some people, genetics or deficiencies cause a “fixed homocysteine rate,” meaning diet and vitamins alone won’t lower it. In those cases, the only real way to balance it is by supporting the pathway that converts homocysteine into glutathione. That’s why reduced, stable glutathione—like VARS Glutathione—is essential, because most products are oxidized and useless by the time you take them. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Your body’s ability to detox depends on one critical pathway—turning homocysteine into glutathione. But for millions with MTHFR or other genetic SNPs, this process is broken, leaving them vulnerable to toxins, inflammation, and cytokine sto

Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which damage the lungs. Research shows raising glutathione can lower these cytokines, yet most products don’t work. VARS Glutathion

Kids with cystic fibrosis often have high levels of inflammatory cytokines like IL-4, IL-5, IL-8, and IL-13, which damage the lungs. Research shows raising glutathione can lower these cytokines, yet most products don’t work. VARS Glutathion