Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance.
Also called: Catechol-O-Methyltransferase
Catecholamines and sensit…
Dr.
Also called: Cystathionine Gamma-Lyase
From homocysteine toward glutathione
Dr. Purser places CTH in the sulfur-handling pathway that connects homocysteine with glutathione production. In that map, CTH concerns the downstream step that …
DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.
Also called: Dihydrofolate Reductase
R…
Encodes an enzyme involved in fatty-acid metabolism.
Also called: Fatty Acid Desaturase 2 / D6D
The form of a fatty acid matters
Dr. Purser teaches FADS genes as a conversion pathway. FADS2 participates in a delta-6 desaturase step in fatty…
FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
Also called: Folate Receptor …
FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors.
Also called: Fat Mass and Obesity-…
Dr.
Also called: Fucosyltransferase 2
The mucosal and microbiome connection
Dr. Purser’s course places FUT2 in its gut–immune map. FUT2 concerns secretor biology and the surface environment of mucosal tissues, helping explain why it appears…
G6PC2 encodes a glucose-6-phosphatase-related protein expressed in pancreatic islet cells. Common variation is associated with differences in fasting glucose regulation; it is not the insulin receptor.
Also called: Glucose-6-Phosphatase Cat…
GAD2 belongs to the glutamate decarboxylase family discussed in the course’s GAD/GABA teaching.
Also called: Glutamate Decarboxylase 2
Another part of the GABA system
GAD2 belongs to the glutamate decarboxylase family discussed in the cours…
Dr.
Also called: Glutamate-Cysteine Ligase Catalytic Subunit
Making glutathione is a process
Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLC supplies the catalytic component of the first enzyme step in glutathione s…
Dr.
Also called: Glutamate-Cysteine Ligase Modifier Subunit
Making glutathione is a process
Dr. Purser groups GCLC and GCLM as glutathione-synthesis machinery. GCLM supplies the modifier component that helps regulate that same glutathione-s…
GDF5 encodes growth differentiation factor 5, a signaling protein involved in skeletal development, joint formation and cartilage biology. Its name does not mean a SNP measures the ability to build muscle.
Also called: Growth Differentiatio…
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