HRH1
Some search terms matchedHRH1 is the gene symbol used for Histamine Receptor H1. This page connects its terminology with the topics in the Purser Wellness teaching library.
Also called: Histamine Receptor H1
Receiving the histamine signal
The Purser genetics refere…
HRH2
Some search terms matchedHRH2 is the gene symbol used for Histamine Receptor H2. This page connects its terminology with the topics in the Purser Wellness teaching library.
Also called: Histamine Receptor H2
Histamine also connects to stomach acid
Dr. Purser’s gene…
IL23R
Some search terms matched…ts the pieces
Dr. Purser includes IL23R in his inflammatory bowel disease and psoriasis teaching. The gene, the cytokine IL-23 and the downstream cytokine IL-17A are related but distinct. An inherited marker does not measure receptor functi…
IL6
Some search terms matched…r in discussions of infection, chronic inflammation and metabolic health, with effects that depend on the context.
Also called: IL-6, Interleukin 6
IL-6 links inflammatory and metabolic signals
IL6 encodes interleukin-6, a cytokine involved…
KIT
Some search terms matched…inase that responds to stem cell factor. It participates in blood-cell development and mast-cell biology, making the exact variant and testing context especially important.
Also called: Kit Proto-Oncogene
A growth receptor with a mast-cell …
MMP3
Some search terms matched…3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.
Also called: Matrix M…
MTHFD1
Some search terms matched… a pathway review should not stop at the word “folate” on a bottle.
How Dr. Purser connects the pieces
The course connects this network to MTHFR, SHMT1 and SLC19A1 and asks about current methylated-vitamin exposure. The practical question i…
MTHFD1L
Some search terms matched…tetrahydrofolate Dehydrogenase 1-Like
A mitochondrial contribution to one-carbon metabolism
The homocysteine chapters include MTHFD1L in the wider folate-related genetic map. MTHFD1L concerns mitochondrial one-carbon metabolism; it is disti…
MTHFR
Some search terms matched…ase, C677T, A1298C, folate, homocysteine
Follow the pathway beyond MTHFR
Dr. Purser teaches MTHFR within a larger folate and homocysteine pathway. MTHFR contributes to production of the folate form used in remethylation; MTR and MTRR connec…
MTR
Some search terms matchedMakes the methionine synthase enzyme, which uses vitamin B12 in the conversion of homocysteine to methionine.
Also called: Methionine Synthase
The B12-dependent step
In Dr. Purser’s teaching map, MTR is the B12-dependent step that converts …
NAT2
Some search terms matched…, which helps process certain drugs and other compounds. Combinations of variants can influence acetylation status; one SNP usually does not tell the entire story.
Also called: N-Acetyltransferase 2
Acetylation and medication handling
NAT2 …
NOS3
Some search terms matchedNOS3 encodes endothelial nitric oxide synthase, which helps blood vessels generate nitric oxide, a signal involved in vascular relaxation. This pathway is distinct from a blood pressure measurement or a diagnosis of vascular disease.
Also c…
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