BCO1, also called BCMO1, helps convert beta-carotene from plant foods into retinal, a form used in vitamin A metabolism. Plant carotenoids and preformed vitamin A therefore enter the pathway at different points.
Also called: BCMO1, Beta-Car…
The practitioner course includes BHMT in Dr.
Also called: BHMT08, Betaine-Homocysteine S-Methyltransferase
Another route through the homocysteine map
The practitioner course includes BHMT in Dr. Purser’s methylation and homocysteine cluster…
BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
Also called: Breast Cancer 1
DNA repair and inherited ca…
BRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
Also called: Breast Cancer 2
DNA repair and inherited ca…
CD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses.
Also called: Cluster of Differentiation 14
How immune ce…
COL5A1 encodes one component of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues.
Also called: Collagen Type V Alpha 1 Chain
Collagen structure, t…
Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance.
Also called: Catechol-O-Methyltransferase
Catecholamines and sensit…
DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.
Also called: Dihydrofolate Reductase
R…
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.
Also called: Estrogen Receptor 1
Estrogen signaling depends on the receptor
ESR1 enc…
Encodes an enzyme involved in fatty-acid metabolism.
Also called: Fatty Acid Desaturase 1 / D5D
The form of a fatty acid matters
Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty…
Encodes an enzyme involved in fatty-acid metabolism.
Also called: Fatty Acid Desaturase 2 / D6D
The form of a fatty acid matters
Dr. Purser teaches FADS genes as a conversion pathway. FADS2 participates in a delta-6 desaturase step in fatty…
Dr.
Also called: Folate Hydrolase 1
Folate handling begins before remethylation
Dr. Purser’s genetic chapters include FOLH1 in folate handling. The earlier genetics reference explains its role in breaking down polyglutamated food folates in…
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