AHCY
Some search terms matched…s that S-adenosylmethionine (SAM) donates methyl groups and becomes S-adenosylhomocysteine (SAH).
Also called: Adenosylhomocysteinase
Methyl-group use leaves another molecule behind
The genetic-architecture chapter explains that S-adenosylm…
AOC1
Some search terms matchedEncodes diamine oxidase, an enzyme involved in breaking down histamine and other amines. DAO is used here as an enzyme nickname; it is also the official symbol of a different gene.
Also called: DAO, Amine Oxidase, Copper Containing 1, Diami…
APOE
Some search terms matchedAPOE encodes a protein that carries lipids between cells. The familiar APOE e2, e3 and e4 groupings depend on the combination of rs429358 and rs7412, not on either marker read in isolation.
Also called: Apolipoprotein E
Lipid transport and …
ATG16L1
Some search terms matched…23R, PEMT and folate-related pathways: immune signaling, membranes/bile and nutrient handling can all enter the same conversation. Those connections do not make an IBS label, Crohn’s disease or another diagnosis interchangeable, and a commo…
BCO1
Some search terms matchedBCO1, also called BCMO1, helps convert beta-carotene from plant foods into retinal, a form used in vitamin A metabolism. Plant carotenoids and preformed vitamin A therefore enter the pathway at different points.
Also called: BCMO1, Beta-Car…
BHMT
Some search terms matchedThe practitioner course includes BHMT in Dr.
Also called: BHMT08, Betaine-Homocysteine S-Methyltransferase
Another route through the homocysteine map
The practitioner course includes BHMT in Dr. Purser’s methylation and homocysteine cluster…
BRCA1
Some search terms matchedBRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
Also called: Breast Cancer 1
DNA repair and inherited ca…
BRCA2
Some search terms matchedBRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
Also called: Breast Cancer 2
DNA repair and inherited ca…
CD14
Some search terms matchedCD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses.
Also called: Cluster of Differentiation 14
How immune ce…
COL5A1
Some search terms matched…mponent of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues.
Also called: Collagen Type V Alpha 1 Chain
Collagen structure, tendons and connective…
DHFR
Some search terms matched…late to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.
Also called: Dihydrofolate Reductase
Recycling folate into usable cellular forms…
ESR1
Some search terms matched…naling is different from the amount of estrogen measured in blood.
Also called: Estrogen Receptor 1
Estrogen signaling depends on the receptor
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling i…
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