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Report teachingAug 16, 2026
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…e pathway Dr. Purser connects IL-23 receptor signaling with inflammatory bowel disease, psoriasis, and inflammatory joint pathways. Targeting IL-23 with a medicine is different from concluding that a genetic result proves excessive receptor…

Report teachingAug 16, 2026
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…eosinophils. Eosinophils are important in some allergic and inflammatory conditions but also have normal immune functions. Follow the pathway Dr. Purser connects IL-5 signaling with eosinophilic asthma and other eosinophil-related conditio…

Report teachingAug 16, 2026
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…in. He also connects homocysteine and oxidative stress with inflammatory activity. IL6 and IL6R are different genes; a variant in either is not equivalent to a measured IL-6 level. Bring these questions to your visit Ask which result is be…

Report teachingAug 16, 2026
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…movement. Follow the pathway Dr. Purser connects IL-8 with inflammatory activity in barrier tissues, blood vessels, and lungs. He discusses monocyte activation, homocysteine, and reactive oxygen species, alongside the separate functions of…

Report teachingAug 16, 2026
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…high level is not specific to sarcoidosis; infection, other inflammatory conditions, and some cancers can also affect it. The pattern of symptoms, imaging, and other tests supplies the missing context. Bring these questions to your visit A…

Report teachingAug 16, 2026
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…tion of a trigger with inflammation, blood-vessel and joint research, and the antioxidant network. Bring these questions to your visit Ask which result is being discussed: a genetic variant, a measured protein level, or a diagnosed conditi…

Report teachingAug 11, 2026
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… factor XI activity, and the distinction between thrombosis research and hemophilia C. The same gene can be associated with very different problems depending on the exact variant and measured function. Bring these questions to your visit A…

Report teachingAug 7, 2026
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…anuloma formation, TNF-alpha, interferon-gamma, and related inflammatory pathways. He also discusses oxidative stress and the distinction between localized skin findings and more widespread disease. Bring these questions to your visit Ask …

Report teachingAug 4, 2026
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… such as ATM and connects DNA damage with oxidative stress. Research on cancer-related pathways does not mean every common RAD50 variant confers a hereditary cancer syndrome. Bring these questions to your visit Ask whether the exact findin…

Report teachingAug 1, 2026
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…e an inflammasome, a protein complex involved in activating inflammatory responses. Follow the pathway Dr. Purser describes the priming and activation steps, caspase-1, IL-1 beta, and IL-18. He connects these steps with gout, metabolic inf…

Report teachingJul 19, 2026
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…ns. Understand the connection Ankylosing spondylitis is an inflammatory condition that often affects the spine and sacroiliac joints. Stiffness, pain, and inflammation can involve more than one part of the body. Follow the pathway Dr. Pur…

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