Let’s explore “2-hour glucose, 75 g OGTT — lab reference”

This report overview covers Toll-like receptor 2, microbial and damage signals, TLR1, TLR6, and MyD88 signaling.

PURSER WELLNESSMTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving SweetsA conversation with Dr. Purser

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

What if the answers you've been searching for aren't found in another prescription—but inside your own cells? Most lab tests tell you what's circulating in your blood. But what if your cells are telling a different story? A Cellular Micro

What if everything you’ve been told about PCOS is missing the real culprit? Homocysteine isn’t just a random lab marker—it may be the hidden thread tying together hormone imbalance, inflammation, and the symptoms so many are struggling to m

PURSER WELLNESSTop Three Benefits of ProgesteroneA conversation with Dr. Purser

Dr. Purser explains the top benefits of natural progesterone. These benefits include: (1) Lowers or eliminates hot flashes (2) Lowers or eliminates night sweats (3) Decreases risk of breast cancer up to 500%. Progesterone may also decrease your risk of cancers overall by as much as 1,000%. Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!

PURSER WELLNESSPlaque Regression with Niacin?A conversation with Dr. Purser

Listen to Dr. Purser in Part 2 of Plaque Regression studies. What are the effects of Niacin and the regression of plaque? Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!

Insulin Resistance Isn’t About Too Little Insulin Most people with type 2 diabetes produce plenty of insulin—the issue is that it can’t get into the cells. When vitamin and nutrient deficiencies develop over time, the insulin receptors stop

PURSER WELLNESSCan You Treat Thyroid During Menopause?A conversation with Dr. Purser

Thyroid health remains essential during menopause. Optimal labs should show FT3 around 4.0 and FT4 near 1.5, and testing through Direct Labs makes it easy to track. Supporting with supplements like Thyromin can help, but only if guided by accurate lab results. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSWhat are the ROOT CAUSES of you symptoms?A conversation with Dr. Purser

🧬 After 15+ years deep in genetics, Dr. Purser sees two root causes over and over again: 1️⃣ Inflammation 2️⃣ Gut & liver dysfunction. Almost every chronic issue—including fibromyalgia, fatigue, and brain fog—ties back to 17 homocysteine SNPs or PEMT mutations. That’s why he built treatment guides, books, and the CMA + Redox + genetic testing combo. If you’ve been told “everything looks normal” but still feel awful, this is where to look next. Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

🥑 Think you’re eating healthy… but still in pain? You might be copper toxic. Avocados, spinach, nuts, seeds—even “superfoods” are loaded with copper. If you’ve got certain genes (like CBS or GAD1/2), your body can’t process it properly, and

🔥 Chronic pancreatitis but don’t drink? You might have a PEMT gene issue stopping you from making enough phosphatidylcholine—critical for protecting your pancreas and liver. Supplement with phosphatidylcholine (1–2 daily) and add VARS Gluta

If you’ve been flagged for PEMT on your NutraHacker or genetic report, don’t just reach for choline—you need phosphatidylcholine. 🧬 This genetic issue is a major cause of NAFLD, NASH, type 2 diabetes, and liver failure if left unaddressed.