…sessment
This chapter asks whether an apparently reassuring laboratory number can hide a nutritional problem. That is a useful question, but the proposed answer must be tested rather than assumed. Protein intake, absorption, medicines, othe…
…raises concerns about sperm production, testicular changes, red-cell counts, acne, fluid retention, blood pressure and injection-site problems. It also makes broader comparative claims about formulations. The useful questions are which risk…
Intracellular testing, or the CMA Cellular Micronutrient Assay, measures over 100 vitamins, minerals, amino acids, and antioxidants inside your cells—not just in your blood. Unlike serum tests, which show short-term levels, intracellular testing reveals what your cells have been missing over the last 100 days. Low levels can mean weak enzymes, non-functioning proteins, and accelerated aging. By identifying deficiencies and matching them with the correct nutrient forms for your genetics, you can target fatigue, anxiety, depression, and other chronic issues at the root. Get your CMA by calling o
MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets
If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.”
In this video, we break down exactly why this happens:
How MTHFR/methylation issues impair ATP (energy) production at the cellular level
Why your body desperately reaches for quick glucose
The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage
The downstream effects on antioxidants, DNA repair, and overall energy
How to finally break the cycle:
Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests)
Why our MTHFR Daily multivitamin was specifically formulated for this
The power of CMA intracellular testing
Intermittent fasting (12–16 hrs)
Fasted cardio (even just a brisk walk)
High-protein, real-food diet with minimal processed sugars
If you’re tired of the sugar rollercoaster and want stable energy, this is for you.
Links:
Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle
Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com
Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily
Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious!
#MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting
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Info: http://www.DanPurserMD.com
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Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.
CMA testing shows what nutrients are inside your cells, not just floating in your blood, giving a true picture of deficiencies. When combined with Redox, it also tracks inflammation markers and oxidative stress—giving a full view of your health and guiding precise supplementation.
Reach out to my practice or visit my site to get going on you CMA with Redox!
801-796-7667 and Info@DanPurserMD.com
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
CMA testing shows what nutrients are inside your cells, not just floating in your blood, giving a true picture of deficiencies. When combined with Redox, it also tracks inflammation markers and oxidative stress—giving a full view of your health and guiding precise supplementation .
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho
A compound involved in cell-membrane signaling.
Also called: Inositol
One nutrient, more than one teaching context
The course includes inositol in nervous-system support alongside magnesium, amino acids and omega fats. The combined Genetic/…
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.
FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements.
FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
Best match puts all-term matches before partial matches and related reading. Identical social posts and matching long titles across other sources are grouped when access is the same. Search covers published titles, descriptions, available article text, report overviews, and the full text of the nutrient, gene and learning-essential reference pages. Books, uploaded chapters and downloads-page reports are searchable through selected editorial guides and topic names; the original files and full book text are not published. Full Drive reports are not copied into search. Substack subscriber titles and public summaries are included; full subscriber content opens on Substack. Video transcripts are added when available.