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MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.

High homocysteine? It’s not the number—it’s the cytokines it triggers (like IL-8) that cause strokes, kidney failure & inflammation. We found 17 gene SNPs + 12 vitamin deficiencies that drive it—and VARS Glutathione helps shut it down.

Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.

If you’ve got genetically high homocysteine, lowering it isn’t as simple as you think. But there’s a way to reduce the inflammation it causes!

Dan Purser MD, renown for his work with MTHFR, chronic fatigue, anxiety, depression, fertility, hormone health, fibromyalgia, and SO MUCH MORE takes on the recent podcast interview of Gary Brecka from 10 Times Health System and Joe Rogan. Mr. Brecka is correct on so many points, but there is still SO MUCH MORE to dive into. The 5 genes he looks at are critical, but there are several to dozens more that need to be addressed. Once you look at genes, you must check out Intracellular Micronutrient Levels. This is THE ONLY way to get the full picture.

What exactly is MTHFR? Here are 10+ tips regarding MTHFR causes, symptoms, diseases, and treatment! Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

It is never easy to lose weight and it is much harder for people with MTHFR. If you have MTHFR, and are struggling with your weight, here is a quick rundown of one reason it may be along with a couple of tips to help you on your weight loss journey! Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

This week Dr. Purser brings on a guest! Lois Schweigert comes to update us on her Facebook page: End Fibromyalgia with Natural Options. Dr. Purser explains the connections between Fibromyalgia and the genetics of MTHFR. Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

This week Dr. Purser introduces his updated version of MTHFR Support Plus - now called MTHFR Endure. Order now at PhysicianDesigned.com. Dr. Purser goes on to discuss the various MTHFR genetic transcription errors, symptoms and ways to treat them. He also covers other top genetic errors that he sees and treats in his practice. If you have fibromyalgia, you most likely have MTHFR errors as well. How does MTHFR connect with COMT errors? Contact us at or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

Dr. Purser covers preventative measures for those with MTHFR should be taking in order to catch the early signs of breast cancer! Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!

Enjoy this interview between Dr. Purser and Dr. Gabe Roberts on the topic of the MTHFR genetic errors! Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!