Let’s explore “body composition”

PURSER WELLNESSOVER-METHYLATION - Are Your B Vitamins Hurting You?A conversation with Dr. Purser

Can the B vitamins you are taking to support energy and methylation eventually make you feel worse? In this video, Jackson Larkin explains what practitioners often call “overmethylation,” a possible adverse response to supplemental methyl donors such as: • 5-MTHF or methylfolate • Methylcobalamin • Trimethylglycine, also called TMG • Multiple overlapping methylation formulas Possible warning signs can include irritability, anxiety, restlessness, insomnia, brain fog, fatigue, and feeling “wired but tired.” These symptoms do not prove that you are overmethylated. They can have many possible causes. The timing of symptoms, your total supplement exposure, nutrient status, genetics, medications, and health history all need to be considered. In this video, we discuss: • Why methylation is essential • How methyl-donor supplements support the body • Why the right vitamin can become the wrong dose • Ingredients to look for on your supplement labels • Why some people may need lower doses or non-methylated forms • How genetics and intracellular nutrient testing can guide a more personalized plan At Purser Wellness, we believe in a Start Low, Go Slow approach. The goal is not to eliminate methylation. The goal is to provide the right form and amount of support for each individual. Learn more or schedule with Purser Wellness: https://danpursermd.com Educational content only. Do not discontinue prescribed or medically necessary supplements without consulting your qualified healthcare professional. #Overmethylation #MTHFR #Methylation #B12 #Methylfolate #VitaminB12 #TMG #BrainFog #FunctionalMedicine #PurserWellness Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSMTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving SweetsA conversation with Dr. Purser

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

PURSER WELLNESSVARS TRIAD | What Does That Mean? | Live with Dan Purser MDA conversation with Dr. Purser

Discover the power of the VARS Triad (also called the REDOX Triad)—Dr. Dan Purser MD’s groundbreaking, patented antioxidant protocol featuring VARS Glutathione, VARS SOD, and VARS Catalase. In this live session, Dr. Purser breaks down what VARS stands for (Validated, Absorbable, Reduced, Stable), how this physician-designed trio supports your body’s natural redox balance, quiets inflammation and cytokines at the root-cause level, and helps overcome genetic challenges like high homocysteine, oxidative stress, and related chronic issues. Perfect for anyone exploring advanced functional medicine and targeted supplementation. Learn more at https://physiciandesigned.com/blogs/glutathione/discover-the-vars-trio-your-bodys-ultimate-antioxidant-powerhouse

PURSER WELLNESSAutism Answered - Root Cause Solved with #1 Reviewed MD in the USAA conversation with Dr. Purser

Hi, I’m Dr. Dan Purser. For too long, autism has been treated as a mystery with only symptom management. In this episode, I break down what I’ve seen consistently in practice: the real root cause behind many cases on the spectrum. It starts with genetic variants (especially MTHFR and related SNPs) that break the transsulfuration pathway. When kids can’t efficiently convert homocysteine into glutathione, they lose their ability to detox heavy metals and environmental toxins. The result is chronic inflammation, oxidative stress, and developmental challenges. The good news? Once we identify these biochemical and genetic imbalances through proper testing, we can intervene at the root with targeted support — restoring methylation, rebuilding glutathione function, and giving the body what it needs to heal. This isn’t theory. It’s the Purser Method® in action. If you’re a parent searching for real answers instead of just labels, this episode is for you. The root cause has been solved. Now let’s talk solutions.

PURSER WELLNESSWhat is MTHFR? What can YOU do about it?A conversation with Dr. Purser

MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.

PURSER WELLNESSWhat Happens If You Have A Gene SNP?A conversation with Dr. Purser

Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.

PURSER WELLNESSGene Types ExplainedA conversation with Dr. Purser

Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.

PURSER WELLNESSWhat Makes A Functional Glutathione?A conversation with Dr. Purser

Most glutathione supplements fail because they break down before your body can use them. VARS Glutathione is different—it’s patented, validated, and proven to raise real intracellular glutathione levels. That means it actually works to calm inflammation, lower cytokines, and protect your cells where it matters most.

PURSER WELLNESSThe Real Problem With CT Scans?A conversation with Dr. Purser

While CT scans are sometimes necessary, the radiation exposure they create can cause oxidative damage in the body. That’s why antioxidants like glutathione are so important—when taken in a validated, reduced form, they help detox and protect against the harmful effects of scans, heavy metals, and chemicals like gadolinium. Dr. Purser’s VARS Glutathione and Nayan Patel’s topical Glutaryl formulas are the only patented, validated glutathiones proven to actually work at this level, helping patients recover quickly from oxidative stress.

PURSER WELLNESSBe Wary Of Glutathione Product Claims!A conversation with Dr. Purser

Many skincare and supplement companies throw around the word “glutathione,” but most of their products don’t actually deliver meaningful amounts—or the right form. For example, a popular serum claims anywhere from 50,000 ppm to just 500 ppm glutathione, which would equal almost nothing per bottle. On top of that, most products use oxidized glutathione, which doesn’t work in the body. That’s what makes VARS Glutathione different—it stays in its reduced, functional form all the way until your cells use it, giving you a real therapeutic dose that actually works.

PURSER WELLNESS🧬 What’s more powerful than glutathione or vitamin C?A conversation with Dr. Purser

Superoxide dismutase (SOD)—your body’s first line of defense against DNA-damaging free radicals. SOD neutralizes superoxide radicals at the source of cellular energy production. But as we age—or if we have genetic SNPs—our ability to make SOD drops. That’s why we created VARS SOD, with over 10,000 IU per dose (most products have less than 240 IU). It’s a game changer for anti-aging, DNA protection, and reducing inflammation at the root.

PURSER WELLNESSPEMT and connection to choline and glutathione!A conversation with Dr. Purser

One of the most powerful nutrients you’ve never heard of? Phosphatidylcholine. It builds the walls of your cells, protects your gut lining, supports nerve function, and even helps your body make bile. If you have a PEMT gene mutation, your body struggles to make it—and that means gut issues, nerve dysfunction, and chronic inflammation.