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MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Dan Purser MD and Jackson Larkin discuss the connections they consider between sugar cravings, cellular energy, and methylation.

Unlock the power of Methionine and Glutathione for true wellness! Discover how these essential nutrients work together to support your body’s natural detox, boost energy, and help you thrive. Ready to take your health to the next level? Let

Dr. Dan Purser literally writes out what glutathione is, why it is important to your body and your cells, and the difference between the useless oxidized version of glutathione (GSSG) and the functional version of glutathione (GSH). Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!

A subscriber post from Purser Wellness on Substack, covering wellness.

MTHFR and methylation SNPs are closely related to the methionine and transsulfuration pathways. Everything in your body is connected and trying to balance out. If you are tired, exhausted, or have unending anxiety, there’s a reason your bod

Riboflavin, methionine, iron, and more. All of these defiencies are intrinsically connected, and some even connect back to MTHFR gene SNPs. You have all these symptoms, but what can you do? Get your CMA Intracellular testing (through my off

MTHFR Daily fills all the holes of the methylation cycle caused by MTHFR and other genes, but what does that mean for you? You are now in a balancing act, filling the deficiencies that have plagued you your whole life while trying not to

SAM e is critical in the methylation cycle of MTHFR, but too much can cause HORRIBLE side effects. Let’s talk.

BIG METHYLATION CYCLE with end of this cycle being to convert homocysteine to glutathione. If any part of this cycle gets blocked due to a missing pathway (snp or error) being always in the way then the glutathione isn't created. BUT also

Think through the nutrition questions before cutting methionine or protein.

Everyone talks about MTHFR. But what if that is only one piece of the puzzle? MTHFR helps process folate, while MTR helps recycle homocysteine back into methionine with the help of vitamin B12. Two genes. Different roles. One interco