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Struggling with high blood pressure that just won’t budge—even with multiple meds? 😩💊 It might be due to genetic issues causing high homocysteine 🧬, which can stiffen your arteries through IL-8 and MCP-1 cytokines 🧪🫀. I’ve seen patients dr

If you suffer with POTS, let’s get you better. A simple blood test will show which deficiencies you have, but specifically will show LOW IRON inside your cells. This is the main culprit and is easily reversible. No excuse, let’s get you bet

Discover the power of Glutathione! This super antioxidant acts like a spear for white blood cells, helping to detoxify by grabbing viruses, metals, and toxins from your system. Glutathione supports liver and kidney function, stabilizes infl

People often ask me the best natural way to lower blood pressure. My answer? Glutathione. High doses can help reduce artery inflammation by stabilizing monocytes that release harmful cytokines, which can lead to high blood pressure. Not a f

What is the best baseline blood test you can get? The CMA intracellular micronutrient assay. Once yo have the results of your intracellular deficiencies, what do you do next? Great news for you, if you buy the consult bundle, you get 30 min

Why do you need glutathione? The Master Antioxidant is needed in every cell for functionality and vitality, but what if you can’t create enough glutathione? If you have MTR, MTRR, GGH, CBS, or MTHFR, you are not going to convert homocyste

PEMT is a genetic error that causes you to not make and phosphatidylcholine. This fatty acid is critical for cell membrane health but you may be critically low in it! Glutathione is critical for the stabilization of the PEMT error. VARS Lip

Three nutrients to help lower your blood pressure: theonine, arginine, and citruline. These three, if you’re deficient in them, may help open and clear arteries and lower blood pressure.

Why do you need an Intracellular Test, versus a standard serum blood test? Intracellular testing shows a snapshot of the current levels within you cells, instead of the levels of vitamins, minerals, and amino acids that are floating in yo

Intracellular testing, or the CMA Cellular Micronutrient Assay, measures over 100 vitamins, minerals, amino acids, and antioxidants inside your cells—not just in your blood. Unlike serum tests, which show short-term levels, intracellular testing reveals what your cells have been missing over the last 100 days. Low levels can mean weak enzymes, non-functioning proteins, and accelerated aging. By identifying deficiencies and matching them with the correct nutrient forms for your genetics, you can target fatigue, anxiety, depression, and other chronic issues at the root. Get your CMA by calling o

MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.” In this video, we break down exactly why this happens: How MTHFR/methylation issues impair ATP (energy) production at the cellular level Why your body desperately reaches for quick glucose The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage The downstream effects on antioxidants, DNA repair, and overall energy How to finally break the cycle: Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests) Why our MTHFR Daily multivitamin was specifically formulated for this The power of CMA intracellular testing Intermittent fasting (12–16 hrs) Fasted cardio (even just a brisk walk) High-protein, real-food diet with minimal processed sugars If you’re tired of the sugar rollercoaster and want stable energy, this is for you. Links: Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious! #MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting Follow Dr. Purser! Info: http://www.DanPurserMD.com Supplements: https://www.PhysicianDesigned.com Books: https://www.amazon.com/-/e/B00BIKSGVQ Facebook: https://www.facebook.com/danpursermd Facebook: https://www.facebook.com/PhysicianDesigned Twitter: https://twitter.com/realdanpursermd YouTube: https://www.youtube.com/danpursermd Instagram: https://www.instagram.com/danpurser.md Pinterest: https://www.pinterest.com/danpursermd

Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.