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Primary ovarian insufficiency describes reduced ovarian function before age 40.

Transverse myelitis involves inflammation in the spinal cord and can affect movement, sensation, and bladder function.

Dr. Purser’s report looks at the immune signals involved in inflammation of the colon.

Follow Dr. Purser’s discussion of folate metabolism and inflammation.

This immune-mediated condition can affect the optic nerves and spinal cord.

A episode from Purser Wellness on Substack, covering hormones, testing and nutrients.

Learn how eosinophils and type 2 immune signals are discussed in this teaching.

Dr. Purser explores questions about primary ovarian insufficiency (POI) and cytokines. The full subscriber post is on Substack.

…ne is part of the body’s antioxidant network. Monocytes are immune cells that can release cytokines when they receive stress or danger signals. Follow the pathway Dr. Purser discusses reactive oxygen species, NF-κB, NLRP3, and the cytokine…

… stress, and the kidney’s filtering structures. He connects immune signaling with reactive oxygen species and antioxidant defenses while keeping these mechanisms distinct from a confirmed cause of kidney failure. Bring these questions to y…

Learn about the interferon and IL-15 pathways described in this teaching.

…red or stressed cells, it can act as a danger signal to the immune system. Follow the pathway Dr. Purser explains the connection between HMGB1, receptors such as RAGE and TLR4, NF-κB signaling, and ongoing tissue inflammation. He also disc…