IFNG encodes interferon gamma, a cytokine involved in cellular immune defense and activation of macrophages. It differs from the Th2 signals more often emphasized in allergic responses.
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What’s searchable?Explore the IFNG promoter variant rs2069705, the -1616 position, STAT4, and questions about interferon-gamma regulation.
Explore the IFNG variant rs2430561, the +874 T/A position, NF-kappa B, and interferon-gamma regulation.
IL12B encodes the p40 subunit shared by IL-12 and IL-23. This makes it an intersection between immune pathways rather than a stand-alone measure of one cytokine.
IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
Explore type I interferon signaling, pain, inflammation, and questions about treatment.
Explore type II interferon, natural killer cells, T lymphocytes, biologic therapies, and related antioxidant pathways.
Explore interleukin-18, caspase-1, the NLRP3 inflammasome, interferon-gamma, and related immune pathways.
Explore skin inflammation, dermal collagen, granulomas, and related immune signals.
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