Learn why a common SNP and a pathogenic BRCA variant are different findings.
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186 resources9 duplicate listings grouped
What’s searchable?BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
BRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
Classify by evidence, zygosity, phenotype, and clinical actionability rather than a numeric range.
Explore rs1801406, BRCA2, DNA repair, cancer-risk interpretation, genetic counseling, and inflammatory signaling; your exact result needs a clinician’s interpretation.
FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors.
Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.
PSEN1 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
PSEN2 encodes a presenilin protein that participates in gamma-secretase, a protein-processing complex. Some pathogenic variants can cause familial Alzheimer’s disease; a listed common marker is not equivalent to that diagnosis.
Explore monoamine oxidase, the MAOA and MAOB genes, rs1137070, rs2072743, rs66323, rs1799836, rs2283729, neurotransmitter metabolism, dietary amines, and treatment research.
Explore interleukin-10, rs1800896, rs1800871, rs1800872, regulatory T cells, and inflammatory regulation.
Explore rs1800925, rs20541, IL-13 receptor terminology, and biologic and antioxidant approaches.
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