BRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
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What’s searchable?CBS helps move homocysteine into the pathway that supplies building blocks for glutathione.
CHDH helps convert choline toward betaine, a nutrient involved in the homocysteine pathway.
Makes an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance.
CTH helps make cysteine, one of the building blocks your body uses to make glutathione.
DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells.
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.
Encodes an enzyme involved in fatty-acid metabolism.
Encodes an enzyme involved in fatty-acid metabolism.
FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors.
GAD2 helps make GABA, a chemical messenger, from glutamate.
GCLC helps make glutathione, an antioxidant your body produces.
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