IL18 encodes interleukin-18, a cytokine that can promote interferon-gamma responses in the appropriate immune context. Its receptor includes components encoded by IL18R1 and IL18RAP.
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What’s searchable?IL2RA encodes the alpha chain of the interleukin-2 receptor, also called CD25. It is involved in immune activation and regulatory T-cell biology; a soluble receptor measurement is distinct from a DNA result.
IL33 encodes interleukin-33, a signal that can act as an alarmin during tissue stress and promote type 2 immune responses. It belongs in a different functional group from chemokines that recruit cells.
IL4 encodes interleukin-4, a cytokine involved in Th2 immune responses and antibody class switching, including pathways related to IgE. It operates alongside IL-5 and IL-13 rather than representing all allergic biology by itself.
Refers to part of the HLA immune-recognition region, rather than one gene. HLA typing requires more detail than a broad region label.
Explore MCP-4, CCR1, CCR2, CCR3, immune-cell recruitment, asthma, allergic rhinitis, and rheumatoid arthritis.
Explore monocyte chemoattractant protein-1, CCR2, monocytes, macrophages, and immune-cell recruitment into tissues.
Explore CXCL13, B-cell and follicular helper T-cell movement, germinal centers, and immune-cell organization.
Explore transsulfuration, methylation, glutathione, genetic variants, cytokines, and possible connections.
Explore interleukin-16, CD4, caspase-3, immune-cell recruitment, and inflammatory signaling.
Explore interleukin-18, caspase-1, the NLRP3 inflammasome, interferon-gamma, and related immune pathways.
Explore interleukin-23 receptor, JAK2, TYK2, STAT3, and related immune signaling.
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