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Transverse myelitis involves inflammation in the spinal cord and can affect movement, sensation, and bladder function.

Dr. Purser’s report looks at the immune signals involved in inflammation of the colon.

Explore the eye inflammation and cytokine connections in Dr. Purser’s report.

Follow Dr. Purser’s discussion of folate metabolism and inflammation.

Proctitis is inflammation of the rectal lining and has several possible causes.

This condition can cause recurring inflammation of cartilage, including the ears, nose, and sometimes the airway.

Scleritis is painful inflammation of the white outer wall of the eye and can occur with other inflammatory conditions.

BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.

BRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.

IL6 encodes interleukin-6, a cytokine involved in immune responses and acute-phase signaling. It can appear in discussions of infection, chronic inflammation and metabolic health, with effects that depend on the context.

TNF encodes tumor necrosis factor, an immune-signaling protein involved in inflammation, host defense and regulation of cell survival. Its name should not be read as proof that a TNF result indicates cancer.

CCL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling.