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Health BlogMar 9, 2022
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…g your gut flora and following a healthy diet. 2. Vitamin D Research has shown that adequate vitamin D levels are crucial to good health. Vitamin D plays many roles in the body. Vitamin D supports the immune system, promotes a healthy infla…

Health BlogOct 14, 2021
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…lished in Circulation. Two-thirds of heart disease clinical research still focuses on men. Women are five times more likely to die from heart disease than breast cancer. Among women, the risk of having a heart attack greatly increases durin…

Books & reading guidesFrom the archive
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… the pieces connect Immune signals and oxidative stress are research topics in pain. Persistent pain can have many causes, so ask which explanation fits your symptoms and findings. Pain is an experience, not one laboratory value Dr. Purser…

Report teachingOct 2, 2026
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Scleritis is painful inflammation of the white outer wall of the eye and can occur with other inflammatory conditions.

Gene referenceSep 23, 2026
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MMP3 encodes matrix metalloproteinase 3, an enzyme involved in breaking down components of the extracellular matrix. Controlled remodeling is part of repair, while excess activity can accompany inflammatory tissue damage.

Gene referenceSep 23, 2026
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PTGS2, commonly called COX-2, encodes an enzyme involved in prostaglandin production. Prostaglandins participate in pain, fever and inflammatory signaling.

Gene referenceSep 23, 2026
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CCL11 encodes eotaxin-1, a chemokine best known for attracting eosinophils. Its receptor relationships connect it to allergic inflammation as well as broader research into immune signaling.

Gene referenceSep 23, 2026
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CXCL13 is a chemokine that attracts cells expressing CXCR5, including B cells. This pairing helps organize immune-cell traffic in lymphoid tissues and some chronic inflammatory settings.

Gene referenceSep 23, 2026
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HMGB1 normally has functions inside the cell nucleus. When released outside cells in particular settings, it can act as a damage-associated molecular pattern, or DAMP, participating in inflammatory signaling.

Gene referenceSep 23, 2026
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IL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one.

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