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…om concentrated curcumin extracts, especially formulas with absorption-enhancing ingredients. What symptoms can—and cannot—tell you There is no established dietary deficiency syndrome for this specific botanical or compound. Symptoms are no…

… explains that S-adenosylmethionine (SAM) donates methyl groups and becomes S-adenosylhomocysteine (SAH). Also called: Adenosylhomocysteinase Methyl-group use leaves another molecule behind The genetic-architecture chapter explains that S-a…

…nd a common variant is not a substitute for a digestive workup. A question to bring to your visit Which part of my history points to inflammation, absorption, bile-related digestion or another cause? Reading your own results Bring your orig…

…an assumed to prove a BCO1 problem. Review dietary sources, absorption and actual nutrient findings before using preformed vitamin A, which can accumulate and requires particular care during pregnancy. A question to bring to your visit Am I…

…-clearance teaching. Check the exact name on your report to follow the right topic. Putting the pieces together For Dr. Purser’s discussion of food-associated histamine reactions and DAO enzyme support, continue to AOC1. DAOA belongs in a d…

…nding can prompt more precise questions about nutrition and absorption, but it does not prove that folate cannot be absorbed or that all digestive symptoms arise from this gene. A question to bring to your visit Are food intake, absorption …

…ther Dr. Purser’s folate notes include FOLR2 as part of the uptake story. The practical teaching is to distinguish nutrient intake, intestinal absorption and cellular transport instead of calling every folate-related result an MTHFR problem…

…nd a common variant is not a substitute for a digestive workup. A question to bring to your visit Which part of my history points to inflammation, absorption, bile-related digestion or another cause? Reading your own results Bring your orig…

…er Dr. Purser notes an indirect connection to homocysteine. Follow that connection through the wider folate network, including MTHFR, MTR and nutrient status, rather than interpreting GGH as a direct homocysteine reading. Some medicines als…

… two best-known MTHFR variants. Putting the pieces together Follow the connection to folate availability and the cellular processes that use one-carbon units. The pathway provides context, but it cannot tell you from the gene name alone whe…

…ahydrofolate Reductase, C677T, A1298C, folate, homocysteine Follow the pathway beyond MTHFR Dr. Purser teaches MTHFR within a larger folate and homocysteine pathway. MTHFR contributes to production of the folate form used in remethylation; …

…ys. That is one reason both nutrition and genetics can come up in a folate conversation. Neither a gene result nor a folate number tells the whole story alone. Putting the pieces together His wider map connects methylation with downstream s…