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Scleritis is painful inflammation of the white outer wall of the eye and can occur with other inflammatory conditions.

This immune-mediated condition can affect the optic nerves and spinal cord.

IL10 encodes interleukin-10, a cytokine that can limit inflammatory responses and help prevent excessive immune-mediated tissue damage. Immune balance includes resolving a response as well as starting one.

Explore multiple sclerosis (MS), central nervous system inflammation, myelin, symptoms, and related immune signals.

Explore cytokines, chemokines, receptors, and related genes on the comprehensive panel, including CD40LG, IL18R1, DDAH1, RAD50, and SLC19A1.

🧬 MTHFR Mutations, High Homocysteine & Autoimmune Disease: The Hidden Root Cause Most Doctors Miss For decades, patients with RA, lupus, MS, Hashimoto’s, and fibromyalgia chase symptom relief with meds that never fix the underlying fire. A

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation . This is not fringe theory. It is the clinical reality I hav

Most people have never heard of homocysteine , yet this small molecule may hold the key to understanding inflammation, cardiovascular disease, neurological problems, and many chronic conditions. For decades, homocysteine was viewed as a toxic substance in the blood. Doctors were taught that lowering it with B-vitamins might reduce heart disease risk. But research results were inconsistent, leaving many physicians unsure whether homocysteine truly mattered. New research and clinical observations are changing that view. We introduce a new framework called the Purser Model , which explains why ho

Most doctors run standard serum blood tests, see a "normal" nutrient level, and send you home. But measuring floating nutrients in your liquid serum is like looking at the paint on a house to see if the plumbing works inside. After reviewing over 40,000 advanced intracellular vitamin lab panels, the truth is clear: intracellular glutathione vs serum levels tell two entirely different stories. Your serum can look completely fine while your cells are completely depleted of the master antioxidant needed to protect your life. The Cytokine Threat When methylation breaks down and homocysteine elevat

Glutathione is part of the body’s antioxidant network.

Explore the allergy response and the immune signals discussed in Dr. Purser’s alpha-gal report.

Explore the cytokine pathways discussed alongside dryness and systemic symptoms.