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HLA-DQA2 is part of the HLA class II region involved in immune recognition. It should not be treated as interchangeable with HLA-DQA1 or as a measurement of how well the immune system fights infections.

KIT encodes a receptor tyrosine kinase that responds to stem cell factor. It participates in blood-cell development and mast-cell biology, making the exact variant and testing context especially important.

VDR encodes the vitamin D receptor, which helps regulate gene activity in response to active vitamin D. A receptor variant does not by itself mean receptors are absent or that the blood vitamin D level is low.

C3 is the gene name for Complement C3. Learn what a specific result could mean and what to ask about it.

CCR3 is the gene name for C-C Motif Chemokine Receptor 3. Learn what a specific result could mean and what to ask about it.

Encodes cubilin, part of a receptor system involved in uptake of the intrinsic-factor–B12 complex.

Refers to part of the HLA immune-recognition region, rather than one gene. HLA typing requires more detail than a broad region label.

TPSAB1 is the gene name for Alpha Tryptase. Learn what a specific result could mean and what to ask about it.

Explore interleukin-1 beta, NLRP3, inflammasome activation, caspase-1, inflammatory conditions, and treatment research.

Explore NAFLD, NASH, MASLD, MASH, hepatitis, the IL-23/IL-17 axis, and liver inflammation.

Explore tumor necrosis factor-alpha, TNFR1, TNFR2, rs1800629, inflammatory signaling, and treatment comparisons in Purser Wellness teaching.

Dr. Purser’s subscriber report on IL-5, cytokine genetics, and the topics discussed in his homozygous IL5 variant report.