Follow the IL-23 and IL-17 conversation in Dr. Purser’s psoriasis report.
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What’s searchable?Learn about the interferon and IL-15 pathways described in this teaching.
Understand the difference between primary and secondary Raynaud’s in this report.
Learn how eosinophils and type 2 immune signals are discussed in this teaching.
Learn how this teaching connects shoulder and hip stiffness with immune signals.
Follow Dr. Purser’s discussion of folate metabolism and inflammation.
This immune-mediated condition can affect the optic nerves and spinal cord.
Dr. Purser discusses interleukins and oxidative stress in cystic fibrosis lung disease.
FOLR2 encodes folate receptor beta, a folate-binding protein expressed in particular cell types, including subsets of immune cells. It is distinct from the FOLR1 receptor and the SLC19A1 reduced folate carrier.
HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type.
HLA-DQA2 is part of the HLA class II region involved in immune recognition. It should not be treated as interchangeable with HLA-DQA1 or as a measurement of how well the immune system fights infections.
KIT encodes a receptor tyrosine kinase that responds to stem cell factor. It participates in blood-cell development and mast-cell biology, making the exact variant and testing context especially important.
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