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🧬 MTHFR Mutations, High Homocysteine & Autoimmune Disease: The Hidden Root Cause Most Doctors Miss For decades, patients with RA, lupus, MS, Hashimoto’s, and fibromyalgia chase symptom relief with meds that never fix the underlying fire. A

— A Guide by the World’s Leading Homocysteine Expert For more than four decades as a practicing physician, I have watched thousands of patients cycle through conventional autoimmune treatments that address symptoms but never touch the fire underneath. Rheumatoid arthritis flares, lupus rashes, multiple sclerosis relapses, Hashimoto’s thyroiditis, fibromyalgia pain—these are not random. They share a common, often overlooked biochemical pathway: MTHFR mutations leading to elevated homocysteine that supercharges autoimmune inflammation . This is not fringe theory. It is the clinical reality I hav

The Overlooked Link Between MTHFR Mutations, Hyperhomocysteinemia, PCOS, Fibromyalgia, Chronic Inflammation, and Renal Decline — and Why Precision Genetic Testing May Be the Missing Step

A sudden spike in folate or homocysteine is rarely caused by supplements. It is most often the result of a hidden infection or minor injury triggering a cytokine surge. Identifying and treating the underlying source is the key to bringing l

Years ago, I watched cystic fibrosis (CF) patients receive nebulized glutathione that didn’t seem to help. Decades later, our team developed and patented the first fully functional, reduced, and stable form — VARS Glutathione. Why does thi

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants, pain and wellbeing.

A subscriber post from Purser Wellness on Substack, covering cytokines and immune signaling, inflammation and antioxidants.

A true functional glutathione would help prevent the cytokine cascade that leads to the cytokine storm with the invisible scourge. It would also help ameliorate the inflammatory response to the displaced heme iron we now know is being found

Sample handling and test methods can change a cytokine result. Compare it with the exact range from your lab and ask why the test was ordered.

Ask your clinician to define genes/analytes, specimen, assay, repeatability, and how results change management.