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What’s searchable?Mayo example age 20-24: M 5.25-20.7; F <0.13-1.08. Declines with age and is method-dependent.
…. Purser follows crystal recognition through NLRP3, caspase-1, and IL-1 beta into inflammatory-cell recruitment. This distinguishes the crystal trigger from the cytokines that carry the inflammatory message. Bring these questions to your v…
…nt gene. Also called: DAO, Amine Oxidase, Copper Containing 1, Diamine Oxidase Histamine: making it, responding to it, clearing it Dr. Purser’s genetics reference places AOC1 in the histamine-clearance part of the gut and immune story. The …
ATG16L1 is involved in autophagy, a process that helps cells recycle parts. Also called: Autophagy-Related 16-Like 1 Cellular recycling meets gut immunity ATG16L1 is involved in autophagy, a process that helps cells recycle parts. It is stu…
BCO1, also called BCMO1, helps convert beta-carotene from plant foods into retinal, a form used in vitamin A metabolism. Plant carotenoids and preformed vitamin A therefore enter the pathway at different points. Also called: BCMO1, Beta-Car…
BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding. Also called: Breast Cancer 1 DNA repair and inherited ca…
COL5A1 encodes one component of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues. Also called: Collagen Type V Alpha 1 Chain Collagen structure, t…
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood. Also called: Estrogen Receptor 1 Estrogen signaling depends on the receptor ESR1 enc…
…n fatty-acid metabolism. Also called: Fatty Acid Desaturase 1 / D5D The form of a fatty acid matters Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty-acid metabolism. This is wh…
FOLH1 helps break down folate from food so it can be absorbed. This is different from the MTHFR step. Also called: Folate Hydrolase 1 Folate handling begins before remethylation Dr. Purser’s genetic chapters include FOLH1 in folate handling…
FOLR1 encodes folate receptor alpha, which helps cells take up folate and has an important role in folate transport at the brain’s barriers. Blood folate and folate availability in the nervous system are not identical measurements. Also cal…
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