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Transverse myelitis involves inflammation in the spinal cord and can affect movement, sensation, and bladder function.

Primary ovarian insufficiency describes reduced ovarian function before age 40.

This immune-mediated condition can affect the optic nerves and spinal cord.

Dr. Purser’s report looks at the immune signals involved in inflammation of the colon.

Follow Dr. Purser’s discussion of folate metabolism and inflammation.

Explore the eye inflammation and cytokine connections in Dr. Purser’s report.

Learn how eosinophils and type 2 immune signals are discussed in this teaching.

…ne is part of the body’s antioxidant network. Monocytes are immune cells that can release cytokines when they receive stress or danger signals. Follow the pathway Dr. Purser discusses reactive oxygen species, NF-κB, NLRP3, and the cytokine…

… stress, and the kidney’s filtering structures. He connects immune signaling with reactive oxygen species and antioxidant defenses while keeping these mechanisms distinct from a confirmed cause of kidney failure. Bring these questions to y…

Learn about the interferon and IL-15 pathways described in this teaching.

Interstitial cystitis or bladder pain syndrome can involve persistent discomfort and urinary symptoms. Understand the connection Interstitial cystitis or bladder pain syndrome can involve persistent bladder discomfort and urinary symptoms.…

…red or stressed cells, it can act as a danger signal to the immune system. Follow the pathway Dr. Purser explains the connection between HMGB1, receptors such as RAGE and TLR4, NF-κB signaling, and ongoing tissue inflammation. He also disc…