MTHFR Daily is so potent it may lead to overmethylation, but don’t worry, we deisgned it so you can back down. With a 4 capsule dose, you can figure out how many are good for you over time. Maybe 1-2 capsules a day is perfect, sometimes you may need 6-8! You will feel it out. Listen to your body, and always feel welcome to reach out to me and my team. We are here to guide you on this journey.