Here's one connection between IC (Interstitial Cystitis) and excess copper irritating the bladder. Copper, in excess, can seriously irritate the bladder. Thus my advice to avoid excess copper in your diet and get on a Low Copper Diet. You can download it from the Facebook Page -- END FIBROMYALGIA WITH NATURAL OPTIONS. Also consider Physician Designed COPPER BALANCE as it helps your (probably dysfunctional) Copper Zinc Metallothionein function better.