Facebook·Published: Oct 10, 2020

FINALLY OUR MTHFR RENEW (previously was our MTHFR SUPPORT) IS BACK IN STOCK!

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FINALLY OUR MTHFR RENEW (previously was our MTHFR SUPPORT) IS BACK IN STOCK!

IT WILL AALSO SOON BE ON AMAZON TOO. GET YOUR ENERGY UP AND WEIGHT DOWN!

If you have one or two of the MTHFR SNPS OR ERRORS you’ll usually want to start on this one (unless I tell you differently).

Grab now at www.physiciandesigned.com

Historically this has been our best seller. Try a bottle and find out why.

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Original sourceDan Purser MD

EXPLORE WITH YOUR CARE TEAM

Supplements to explore

Compare the products below, including their ingredients and available forms. Your care team can help you choose one or more options for your needs.

COMPARE YOUR OPTIONS

Methylation support

Dr. Purser discusses these supplements in relation to MTHFR.

MTHFR Daily and Hydroxy B12 + Folinic Acid are alternatives. Your folate, vitamin B12, and genetic results can help your clinician choose between them.

MTHFR DailyPhysician DesignedView product

Hydroxy B12 + Folinic AcidPhysician DesignedView product

Want to understand your own findings?Genetic testing + consultation

Tell your care team which supplements and medicines you already take. Check the product page for current ingredients, prices, and availability.

ONE MORE CONNECTION MADE

Keep your curiosity going.

A LITTLE CLARITY

Understand the terms

Open a short reference guide.

MTHFR→

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Your MTHFR starting point

Mentions mthfr.

Genetics topic

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Genetics & methylation

Make sense of the vocabulary. Explore MTHFR, genetic variants, and the conversations around methylation.

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More to explore

A term in this discussion

PURSER WELLNESSMTHFRFrom the reading room

Gene referenceSep 23, 2026

MTHFR

Makes an enzyme that helps produce a form of folate used in the processing of homocysteine. Common variants are different from rare variants that cause severe MTHFR deficiency.

Genetics

MTHFR C677T Symptoms & The Methylation Paradox: What Your Doctor Missed

If you’ve been struggling with severe chronic fatigue, unexplained anxiety, or cardiovascular red flags, your genes might be trying to tell you something. Millions of patients walk out of traditional clinics with normal blood tests, only to be told their crippling symptoms are "all in their head." If you carry the C677T variant, you aren't crazy—you are dealing with a breakdown in cellular biochemistry. The Problem With Synthetic Folic Acid The standard advice from standard doctors is to take synthetic folic acid. For someone with the C677T genetic mutation, this is disastrous. Your enzyme pat

Genetics

Vitamin B12 (Cobalamin)

Needed for nerve function, DNA production and healthy red blood cells.

Testing

Vitamin B2 (Riboflavin)

Forms enzyme helpers used in energy metabolism.

Testing