THE PURSER WELLNESS LIBRARY
4 chapters, at your pace
1292 discoveries for your curiosity186 matching listings grouped; alternative sources stay available.
What’s searchable?BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding. Also called: Breast Cancer 1 DNA repair and inherited ca…
BRCA2 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding. Also called: Breast Cancer 2 DNA repair and inherited ca…
CD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses. Also called: Cluster of Differentiation 14 How immune ce…
DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate system, distinct from MTHFR and folate transport into cells. Also called: Dihydrofolate Reductase R…
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood. Also called: Estrogen Receptor 1 Estrogen signaling depends on the receptor ESR1 enc…
FTO is studied in relation to body weight and energy balance. Common variants can contribute to population-level differences in obesity susceptibility, alongside many other genes and environmental factors. Also called: Fat Mass and Obesity-…
GDF5 encodes growth differentiation factor 5, a signaling protein involved in skeletal development, joint formation and cartilage biology. Its name does not mean a SNP measures the ability to build muscle. Also called: Growth Differentiatio…
GGH encodes gamma-glutamyl hydrolase, which removes glutamate residues from folate compounds. This affects folate handling and helps explain why folate metabolism includes retention and processing as well as intake. Also called: Gamma-Gluta…
HFE helps regulate iron absorption through signaling that influences hepcidin. The commonly discussed C282Y and H63D variants correspond to rs1800562 and rs1799945. Their implications depend on the combination present and clinical findings.…
HLA-DQA1 contributes to an HLA-DQ protein that presents antigen fragments to CD4 T cells. HLA-DQ function depends on pairing with an HLA-DQB chain, so an isolated marker is not a complete HLA type. Also called: HLADQA1, Human Leukocyte Anti…
KIT encodes a receptor tyrosine kinase that responds to stem cell factor. It participates in blood-cell development and mast-cell biology, making the exact variant and testing context especially important. Also called: Kit Proto-Oncogene A …
MAOB encodes monoamine oxidase B, an enzyme involved in breaking down monoamine compounds, including dopamine. It does not simply build dopamine, and a DNA marker is not a neurotransmitter measurement. Also called: MAO-B, Monoamine Oxidase …
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