Free T4 — lab reference
Some search terms matchedBinding abnormalities and severe illness may affect some free-hormone assays.
THE PURSER WELLNESS LIBRARY
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What’s searchable?Binding abnormalities and severe illness may affect some free-hormone assays.
Useful in selected hyperthyroid states; not a sensitive stand-alone test for hypothyroidism.
Affected by thyroid-binding globulin, pregnancy, estrogen, and medications.
Affected by binding proteins and nonthyroidal illness.
No broadly accepted treatment target. Dr. Purser to define whether and how this is used.
Assay-specific. Positive result supports thyroid autoimmunity but does not determine treatment alone.
Assay-specific. Also affects thyroglobulin tumor-marker interpretation.
Use the exact assay cutoff. Helpful in selected Graves disease questions.
Not a general thyroid wellness target. Use tumor follow-up, thyroid anatomy, and antibody status.
Morning fasting collection is preferred when practical. Day-to-day variation is substantial.
Interpret with iron, transferrin saturation, and ferritin.
Negative acute-phase reactant; affected by liver function and nutrition.
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