Unpacking Leucovorin, Homocysteine, and Glutathione in Autism
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THE PURSER WELLNESS LIBRARY
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What’s searchable?A post from Purser Wellness on Substack, covering inflammation and antioxidants, mind, mood, and sleep.
Did you know your MTHFR gene can impact your homocysteine levels? High homocysteine is linked to heart and brain health—understanding this connection could be the key to solving your mystery medical problems that no doctor or study has been
Did you know your homocysteine genes could be the missing link to better health? Discover why understanding these genes matters for your heart, brain, and overall wellness. Knowledge is power—let’s unlock your healthiest self together!
Questions on Homocysteine and why having homocysteine could be causing a majority of your health issues...
Homocysteine is treatable and you're not crazy! If you've been made to feel crazy by your doctor or the medical community about your homocysteine genetics, Dr. Dan Purser MD believes you! Your homocysteine is treatable!
High homocysteine often shows up first as widespread inflammation—pain all over, poor circulation, or even early warning signs of cardiovascular problems like stroke and heart attack. The best way to know for sure is through testing: a blood test can measure homocysteine directly, while a CMA with Redox uncovers the vitamin deficiencies driving it. For genetic causes, the DRP Genetics panel screens 15–16 of the 17 known SNPs that can cause permanently high homocysteine. If your levels are fixed by genetics, reduced glutathione and targeted B vitamins (like MTHFR Daily) are key to balancing the
High homocysteine? It’s not the number—it’s the cytokines it triggers (like IL-8) that cause strokes, kidney failure & inflammation. We found 17 gene SNPs + 12 vitamin deficiencies that drive it—and VARS Glutathione helps shut it down.
Homocysteine is nasty — but here’s the truth no one tells you. It doesn’t kill you directly — it triggers white blood cells to release IL-8 and MCP-1, causing inflammation, kidney failure, heart attacks, and strokes. Most doctors don’t even check it anymore, thinking there’s no fix. But there is. Whether from 17 genetic SNPs or 12 vitamin deficiencies (like B6 or B12), you can address it by supporting your body’s ability to convert homocysteine into glutathione.
If you’ve got genetically high homocysteine, lowering it isn’t as simple as you think. But there’s a way to reduce the inflammation it causes!
High homocysteine levels can lead to inflammation, joint and muscle pain, and even shifting pain throughout the body. It’s also linked to birth defects and chronic kidney failure, and can raise blood pressure. Six genetic SNPs (like MTR, MTRR, and CBS) and MTHFR mutations (like C677T) can prevent homocysteine from converting into glutathione, which is essential for keeping inflammation in check. Plus, 12 vitamin deficiencies may temporarily raise homocysteine levels, so addressing these deficiencies is key.
Dr. Purser gives insights how to recognize if you have a high homocysteine level. Learn how to improve your level if you experience any of these signs! Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!
Does a normal homocysteine level imply that you don't need to treat MTHFR? Find out in this video! Contact us at (801) 796-7667 or info@danpursermd.com for help. Check back often for the newest updates!
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