THE PURSER WELLNESS LIBRARY
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What’s searchable?MTHFR is one of the most studied genetic SNPs, with the two main variants being C677T and A1298C. These changes reduce the body’s ability to process folate and make energy, leaving people exhausted and deficient in key nutrients. Specialized folates, B12 forms, and glutathione can bypass the blockages, and products like MTHFR Daily were designed specifically to fill these nutrient gaps so patients can restore energy and thrive.
What I see again and again is an inability to detox caused by failures in the Transsulfuration Pathway. This is your pathway that converts homocysteine to glutathione. If you have MTHFR or 16 other Gene SNPs, you will have problems with this pathway.
Genetic SNPs are tiny changes in your DNA that can drastically affect how well your enzymes and proteins work. For example, being homozygous for MTHFR C677T leaves that enzyme functioning at only about 30% efficiency, which can drain your energy and impair folate processing. Similarly, errors in SOD genes reduce your body’s ability to neutralize free radicals. While we can’t change your genes, we can work around them by identifying these weaknesses and filling the gaps with targeted nutrition and supplementation—helping your body function closer to its full potential.
Your genetic results might list “wild type,” “heterozygous,” or “homozygous,” but what does that mean? Wild type means both copies of your gene are normal, heterozygous means one is normal and one has a change, and homozygous means both copies have the same change. With genes like MTHFR, these variations can affect how efficiently your body processes nutrients like folate—sometimes cutting function by 40–70%—which is why targeted nutrition and testing matter.
Superoxide dismutase (SOD)—your body’s first line of defense against DNA-damaging free radicals. SOD neutralizes superoxide radicals at the source of cellular energy production. But as we age—or if we have genetic SNPs—our ability to make SOD drops. That’s why we created VARS SOD, with over 10,000 IU per dose (most products have less than 240 IU). It’s a game changer for anti-aging, DNA protection, and reducing inflammation at the root.
High homocysteine? It’s not the number—it’s the cytokines it triggers (like IL-8) that cause strokes, kidney failure & inflammation. We found 17 gene SNPs + 12 vitamin deficiencies that drive it—and VARS Glutathione helps shut it down.
If you’ve got genetically high homocysteine, lowering it isn’t as simple as you think. But there’s a way to reduce the inflammation it causes!
Crohn’s Disease & Ulcerative Colitis: The Missing Link? Did you know there’s a genetic condition, PEMT, that may be a major factor in Crohn’s disease and ulcerative colitis? If you have it, your body struggles to produce phosphatidylcholine, a critical compound for gut and liver health. Research shows supplementing with phosphatidylcholine and glutathione can make a huge difference in managing these conditions.
What exactly is MTHFR? Here are 10+ tips regarding MTHFR causes, symptoms, diseases, and treatment! Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!
For 35 years now, I deal with root cause illnesses all day, every day. After advising several hundred patients with IC, I believe there is no way to cure it — mainly because it is mostly genetic in root cause. But there are a lot of things you can do to live more healthy lifestyle and have very few, if any symptoms (significantly fewer). Here are 10+ ideas for you to improve your quality of life while living with interstitial cystitis. Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!
It is never easy to lose weight and it is much harder for people with MTHFR. If you have MTHFR, and are struggling with your weight, here is a quick rundown of one reason it may be along with a couple of tips to help you on your weight loss journey! Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!
Dr. Purser talks about a meta-analysis where correlations are drawn between Crohn's disease, ulcerative colitis, inflammatory bowel diseases, and B12 folate deficiencies. However, it is unclear how each are directly related. PubMed Study: https://pubmed.ncbi.nlm.nih.gov/28406440/ Contact us at (801) 796-7667 or info@danpursermd.com for help. Subscribe to stay up-to-date with new content!
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