…y at different points.
Also called: BCMO1, Beta-Carotene Oxygenase 1
From beta-carotene to vitamin A
BCO1, also called BCMO1, helps convert beta-carotene from plant foods into retinal, a form used in vitamin A metabolism. Plant carotenoids …
…Betaine-Homocysteine S-Methyltransferase
Another route through the homocysteine map
The practitioner course includes BHMT in Dr. Purser’s methylation and homocysteine cluster. BHMT provides a betaine-dependent route for converting homocyste…
BRCA1 helps repair damaged DNA. Clinically classified pathogenic variants can affect inherited cancer risk; a common SNP or a variant of uncertain significance is a different finding.
Also called: Breast Cancer 1
DNA repair and inherited ca…
…alled: Cystathionine Beta-Synthase
From homocysteine toward glutathione
Dr. Purser places CBS in the sulfur-handling pathway that connects homocysteine with glutathione production. In that map, CBS concerns the first step moving homocystein…
CD14 helps immune cells recognize microbial components, including bacterial lipopolysaccharide, as part of innate immune signaling. This places it upstream of some cytokine responses.
Also called: Cluster of Differentiation 14
How immune ce…
COL5A1 encodes one component of type V collagen, which helps organize collagen fibers. It connects to the strength and structure of tendons, skin and other connective tissues.
Also called: Collagen Type V Alpha 1 Chain
Collagen structure, t…
…an enzyme that helps break down catechol compounds, including some neurotransmitters. A common variant does not by itself explain mood, attention or stress tolerance.
Also called: Catechol-O-Methyltransferase
Catecholamines and sensitivity
…
Dr.
Also called: Cystathionine Gamma-Lyase
From homocysteine toward glutathione
Dr. Purser places CTH in the sulfur-handling pathway that connects homocysteine with glutathione production. In that map, CTH concerns the downstream step that …
…rt into cells.
Also called: Dihydrofolate Reductase
Recycling folate into usable cellular forms
DHFR helps reduce folic acid and dihydrofolate to tetrahydrofolate-related forms used in cellular metabolism. This is one part of the folate sys…
ESR1 encodes estrogen receptor alpha, which helps cells respond to estrogen. Receptor signaling is different from the amount of estrogen measured in blood.
Also called: Estrogen Receptor 1
Estrogen signaling depends on the receptor
ESR1 enc…
…5D
The form of a fatty acid matters
Dr. Purser teaches FADS genes as a conversion pathway. FADS1 participates in a delta-5 desaturase step in fatty-acid metabolism. This is why plant-based precursor fats and preformed long-chain omega-3s sh…
Dr.
Also called: Folate Hydrolase 1
Folate handling begins before remethylation
Dr. Purser’s genetic chapters include FOLH1 in folate handling. The earlier genetics reference explains its role in breaking down polyglutamated food folates in…
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