The Purser genetics reference places CHDH in choline metabolism, while the combined SOP asks clinicians to consider CHDH alongside PEMT and FADS findings.
This report overview covers interleukin-6, C-reactive protein (CRP), the acute-phase response, rheumatoid arthritis, and the conditions discussed in the report.
MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets
If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.”
In this video, we break down exactly why this happens:
How MTHFR/methylation issues impair ATP (energy) production at the cellular level
Why your body desperately reaches for quick glucose
The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage
The downstream effects on antioxidants, DNA repair, and overall energy
How to finally break the cycle:
Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests)
Why our MTHFR Daily multivitamin was specifically formulated for this
The power of CMA intracellular testing
Intermittent fasting (12–16 hrs)
Fasted cardio (even just a brisk walk)
High-protein, real-food diet with minimal processed sugars
If you’re tired of the sugar rollercoaster and want stable energy, this is for you.
Links:
Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle
Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com
Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily
Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious!
#MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
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What if the answers you've been searching for aren't found in another prescription—but inside your own cells?
Most lab tests tell you what's circulating in your blood. But what if your cells are telling a different story?
A Cellular Micro
Dan Purser MD interviews a patient with a brutal sarcoidosis case involving sky-high SIL2R cytokines, GI sarcoid, heart damage, and years of being dismissed by doctors. After spleen removal, repeated ER visits, and nitroglycerin dependence, he finally found answers.
Learn how cytokine testing and the VARS Trio (Glutathione + SOD + Catalase) led to rapid improvement — going from bedridden fear to playing with grandkids in just weeks.
This episode highlights the power of root-cause medicine for complex inflammatory conditions and offers hope for those who feel lost in the system.
Perfect for listeners dealing with sarcoidosis, chronic inflammation, autoimmune issues, or cytokine-related symptoms.
#Sarcoidosis #Cytokines #VARS #PurserWellness #ChronicIllnessRecovery
Follow Dr. Purser!
Info: http://www.DanPurserMD.com
Supplements: https://www.PhysicianDesigned.com
Books: https://www.amazon.com/-/e/B00BIKSGVQ
Facebook: https://www.facebook.com/danpursermd
Facebook: https://www.facebook.com/PhysicianDesigned
Twitter: https://twitter.com/realdanpursermd
YouTube: https://www.youtube.com/danpursermd
Instagram: https://www.instagram.com/danpurser.md
Pinterest: https://www.pinterest.com/danpursermd
🌾 Why has gluten intolerance exploded since the 1970s?
It’s not just the bread.
In my latest blog I lay out the clear timeline: Roundup (glyphosate) was introduced in 1974… and the rise in celiac disease and gluten sensitivity has tracked
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