…mportant clinical questions concern kidney-function trends, urine findings, symptoms and outcomes over time. Chronic kidney disease also has established contributors, including diabetes and high blood pressure, which must not disappear from…
Intracellular testing, or the CMA Cellular Micronutrient Assay, measures over 100 vitamins, minerals, amino acids, and antioxidants inside your cells—not just in your blood. Unlike serum tests, which show short-term levels, intracellular testing reveals what your cells have been missing over the last 100 days. Low levels can mean weak enzymes, non-functioning proteins, and accelerated aging. By identifying deficiencies and matching them with the correct nutrient forms for your genetics, you can target fatigue, anxiety, depression, and other chronic issues at the root. Get your CMA by calling o
The Purser genetics reference places CHDH in choline metabolism, while the combined SOP asks clinicians to consider CHDH alongside PEMT and FADS findings.
MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health.
While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status c
This report overview covers HbA1c, red blood cell turnover, hemoglobin variants, blood loss, hypoglycemia, and the factors the source discusses when interpreting a low A1C result.
MTHFR gene variants can affect how your body processes folate and methylation, key factors in overall health.
While they don’t directly cause blood sugar crashes, understanding your genetics, nutrition, sleep, stress, and nutrient status
This report overview covers dimethylarginine dimethylaminohydrolase 1 (DDAH1), asymmetric dimethylarginine (ADMA), nitric oxide, blood vessels, and the cardiovascular pathways discussed in the source.
MTHFR & The Never-Ending Sugar Crash Cycle: Why You’re Always Tired & Craving Sweets
If you have an MTHFR variant (C677T or A1298C), you may constantly battle fatigue, sugar cravings, and energy crashes — even when you’re “doing everything right.”
In this video, we break down exactly why this happens:
How MTHFR/methylation issues impair ATP (energy) production at the cellular level
Why your body desperately reaches for quick glucose
The vicious cycle of blood sugar spikes → insulin crashes → more cravings & fat storage
The downstream effects on antioxidants, DNA repair, and overall energy
How to finally break the cycle:
Targeted supplementation that fills methylation “holes” (what we learned from 15–20k intracellular tests)
Why our MTHFR Daily multivitamin was specifically formulated for this
The power of CMA intracellular testing
Intermittent fasting (12–16 hrs)
Fasted cardio (even just a brisk walk)
High-protein, real-food diet with minimal processed sugars
If you’re tired of the sugar rollercoaster and want stable energy, this is for you.
Links:
Read the full Substack article → https://danpursermd.substack.com/p/the-mthfrsugar-craving-cycle
Get your CMA intracellular testing & genetics done → Call our office or visit danpursermd.com
Shop MTHFR Daily → https://physiciandesigned.com/products/mthfr-daily
Have an MTHFR variant? Drop your genotype (heterozygous/homozygous) in the comments — I’m always curious!
#MTHFR #SugarCravings #Methylation #ChronicFatigue #Energy #PurserWellness #FunctionalMedicine #IntermittentFasting
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