Plasma free metanephrines — lab reference
In the reference guideSupine collection and stress control improve specificity; use exact lab cutoffs.
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What’s searchable?Supine collection and stress control improve specificity; use exact lab cutoffs.
Normal <100; prediabetes 100-125; diabetes ≥126 on confirmatory testing unless unequivocal hyperglycemia.
Diabetes may be diagnosed at ≥200 with classic symptoms or hyperglycemic crisis.
Binding abnormalities and severe illness may affect some free-hormone assays.
Useful in selected hyperthyroid states; not a sensitive stand-alone test for hypothyroidism.
Recent supplementation can elevate; very high values may be clinically relevant.
Highly preanalytic-sensitive. Fasting, processing, and recent intake matter.
Mayo example age 20-24: M 5.25-20.7; F <0.13-1.08. Declines with age and is method-dependent.
Often used when total PSA is in an indeterminate zone. Use the performing-lab risk table.
Direct renin and plasma renin activity are not interchangeable.
Specify whole blood, RBC, plasma, or intracellular method. Preanalytic handling is critical.
RBC, plasma, and cellular assays are not interchangeable.
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